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Founding Machine Learning Engineer

Bindwell

Bindwell

Software Engineering
USD 150k-300k / year + Equity
Posted on Oct 17, 2025

Bindwell

Discovering new pesticides with AI

Founding Machine Learning Engineer

$150K - $300K0.50% - 2.50%San Francisco, CA, US
Job type
Full-time
Role
Engineering, Machine learning
Experience
Any (new grads ok)
Visa
US citizen/visa only
Skills
Torch/PyTorch, Machine Learning, Data Analytics
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Tyler Rose
Founder
Tyler Rose
Founder

About the role

We’re fundamentally building a system that replaces a lab technician + physics with a single neural network. This role exists to help build the backbone of that: building foundational biochemistry models and the continuous data feedback loop between model predictions and physical experiments. This role doesn’t require biology knowledge, just solid fundamentals in machine learning.

What you’ll work on:

  • Use your understanding of machine learning to develop models foundational to eventually replacing the need for wet-lab experiments.
  • Design, train, and refine foundational biomolecular interaction models (architecture design)
  • Assemble high-quality training data and build autonomous data collection systems.
  • Analyze the generalization and weaknesses in our models to inform data-generation strategy.
  • Lead the design of future models to replace every part of chemical R&D.

Requirements:

  • Solid practical ML engineering and software engineering fundamentals (Python, PyTorch/JAX/TensorFlow, NumPy/SciPy)
  • Proven track record of designing, building, and validating novel ML model architectures and training techniques.
  • Strong foundation in mathematics, algorithms, statistics, and data science principles.
  • Familiar with SQL and building datasets for ML.

Nice to have:

  • Experience working with biochemical or structural biology datasets
  • Exposure to foundation models in bio (e.g., AlphaFold, ESM, RoseTTAFold, ProtBert).
  • Experience working with LLM agents
  • Experience managing large training runs on GPU clusters.

What we offer:

  • Work directly with both founders in a small highly technical fast paced ML engineering team
  • Ownership of foundational ML infrastructure and research
  • A mission that matters: enabling a safer, more sustainable future in agriculture through better models.

About Bindwell

We use AI to discover new pesticides, because the ones we have now are failing — pests keep evolving, and the chemicals kill too many other things (like humans). Our models replace slow, expensive lab work, letting us discover new molecules 100× faster. Our first pesticide targets a Spodoptera with a novel mode of action. We’re a small team of young engineers from Caltech & Wolfram Research, with experience in drug discovery ML models, rebuilding agrochemical R&D around AI.