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Data/Software Engineer

Mantra Bio

Mantra Bio

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See open jobs at Mantra Bio.
Software Engineering
South San Francisco, CA, USA
Posted on Friday, December 15, 2023

About Mantra Bio

At Mantra Bio we seek to create better medicines by developing next generation biologics based on our leading proprietary exosome engineering platform, REVEAL™. REVEAL™ integrates in silico computational biology and wet-lab automation to enable the rational design of engineered exosome therapeutics directed at a wide range of tissue and cellular targets. The foundation of our success is our truly interdisciplinary team who work collaboratively to accelerate therapeutic development. As a team, we value Self-Empowerment, Candor, Curiosity, and Collaboration and consider our human-centric culture to be our most important asset. We are proud to count 8VC, Viking, Samsung Securities, Illumina, Allen & Company and TenCent among our investors. Mantra Bio operates out of a newly constructed state-of-the-art facility in Oyster Point, South San Francisco.


  • Use appropriate machine learning and statistical methods to gain insights from our experimental data and publicly available proteomic, transcriptomic, and genomic resources
  • Work with target validation and protein scientists to generate hypotheses and coordinate execution of wetlab and drylab experiments to efficiently test these hypotheses
  • Critically evaluate computational and wetlab assay methods in publications used as evidence for locational protein targets
  • Effectively use public datasets and guide generation of internal experimental data to characterize and evaluate locational protein targets
  • Develop novel computational methods as needed to advance our understanding of interactions between EVs and locational protein targets
  • Create appropriate visualizations and tools to enable scientists to explore and gain actionable insights from the output of your algorithms
  • Collaborate with other Data Scientists on models, algorithms, and tools
  • Plan, prioritize, and coordinate tasks across multiple projects

What we are looking for

  • Minimum of 1-2 years of experience in this role (Bootcamp alone is not sufficient).
  • Ensure the ETL process; data is clean, reliable, and accessible to our Data Scientists and Research Scientists
  • Ability to design, implement, and update PostgreSQL and BigQuery database schemas
  • Build simple database-driven web apps using lightweight open source packages
  • Collaborate with Data Scientists and Research Scientists to create or modify databases, dashboards, libraries, and pipelines to meet their needs
  • Support our machine learning and data analysis pipelines
  • Participate in thoughtful code reviews with our other engineers

Required Technical Skills

  • Experience designing, maintaining and deploying relational databases in a professional setting using SQLAlchemy
  • Experience writing complex SQL queries
  • Proven ability to work with varied cloud data infrastructures
  • Proficient in Python, including experience with Pandas and scipy
  • Experience with database schema versioning tools such as Alembic
  • Experience building web apps in Python with Flask, Django, or FastAPI
  • Familiarity with scripting in Linux operating systems
  • Comfortable with frequent, incremental code testing and deployment
  • Comfortable keeping versioned code using Git

Nice to have skills

  • Previous employment in a biotech/pharma or healthcare
  • Basic knowledge of biology
  • Experience building internal APIs
  • Experience scripting within Docker containers
  • Comfortable using Jira for task management and Confluence for documentation
  • Familiarity with CircleCI or a similar tool for continuous development
  • Experience with Kubernetes or similar container orchestration frameworks
  • Experience provisioning cloud resources (GCP)

Required soft skills

  • Appreciates and clearly communicates to stakeholders the tradeoffs between using out-of-the-box cloud tools or the basic tools under those “skins”
  • Enjoys problem solving in a collaborative environment, with an interdisciplinary team.
  • Self-starter who identifies problems and opportunities and then presents potential solutions to the company
  • Thrives in an environment where everyone is personally accountable for their accomplishments and setbacks, and where we also support each other
  • Values receiving and giving constructive feedback
  • Excellent written and verbal communication skills

Mantra Bio’s Culture:

At Mantra Bio, we value Self-Empowerment, Candor, Curiosity, and Collaboration. We take pride in being a human centric, collaborative workplace that brings humble and wildly intelligent people together to build the next revolution in therapeutics. We believe that a great team makes a successful company and we trust each team member to do what’s best for the organization. We believe that a culture of feedback in an environment of empathy and respect is essential to cultivating curiosity and learning, while also leading to personal growth and the growth of our organization. We love handing out Kudos, being creative, and celebrating our success together. We are committed to creating a diverse and inclusive environment and we are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

Compensation Range:

$110.000 - $140.000 depending on your experience


  • Comprehensive health benefits package
  • 401k
  • Meaningful stock option grants
  • Flexible PTO and year-end shutdown
  • Generous Parental Leave program
  • Growth-oriented professional development opportunities
  • Team-building events
  • Fully stocked kitchen

This job is no longer accepting applications

See open jobs at Mantra Bio.